Personalized P2Y12 Inhibitor Treatment

Personalized antiplatelet therapy with P2Y12 receptor inhibitors: benefits and pitfalls

Antiplatelet therapy with P2Y12 receptor inhibitors has become the cornerstone of medical treatment in patients with acute coronary syndrome, after percutaneous coronary intervention and in secondary prevention of atherothrombotic events. Clopidogrel used to be the most broadly prescribed P2Y12 receptor inhibitor with undisputable benefits especially in combination with aspirin, but a considera...

Restoring platelet function in patients on P2Y12 receptor inhibitor treatment: still some issues to be solved!

P2Y12 Inhibitor Pre-Treatment in Non-ST-Elevation Acute Coronary Syndrome: A Decision-Analytic Model

Current guidelines recommend initiation of a P2Y12 inhibitor for all patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) at the time of diagnosis (pre-treatment); however, there are no randomized trials directly comparing pre-treatment with initiation at the time of angiography to support this practice. We explore clinical and institutional parameters potentially associated with b...

comparison of higher-order aberrations after personalized treatment versus personalized treatment advanced photorefractive keratectomy for myopia and myopic astigmatism

purpose: the aim of this study was to compare higher-order aberrations between personalized treatment (pt) versus personalized treatment advanced (pta) photorefractive keratectomy (prk) for myopia and myopic astigmatism. methods: in this clinical trial, 80 eyes of 40 patients who met inclusion criteria were enrolled. they underwent prk using pt or pta algorithm randomly. higher-order aberration...

اعوجاج‌های رده بالا پس از فتورفرکتیوکراتکتومی‌ به دو روش Personalized Treatment و Personalized Treatment Advanced در بیماران نزدیک‌بین و نزدیک‌بین آستیگمات

هدف: مقایسه اعوجاج‌های رده بالا پس از فتورفرکتیوکراتکتومی‌ با دو روش PT و PTA در بیماران نزدیک‌بین و نزدیک‌بین آستیگمات. روش پژوهش: در این مطالعه کارآزمایی بالینی، 80 چشم با توجه به معیارهای ورود به مطالعه، انتخاب و به صورت تصادفی در دو گروه 40 چشمی‌ تحت فتورفرکتیوکراتکتومی با روش PT یا PTA قرار گرفتند. دید اصلاح نشده، دید اصلاح شده، رفراکشن آشکار، معادل کروی، فاکتورQ ، اعوجاج‌های کروی و اعوجاج...